Yayınlar

1. Chavira-Ramos, K., Orozco-Morales, M., Karasu, Ç. et al. URB597 Prevents the Short-Term Excitotoxic Cell Damage in Rat Cortical Slices: Role of Cannabinoid 1 Receptors. Neurotox Res 39, 146–155 (2021). https://doi.org/10.1007/s12640-020-00301-1

2. Hurtado-Díaz ME, Estrada-Valencia R, Rangel-López E, Maya-López M, Colonnello A, Galván-Arzate S, Verstraeten SV, Karasu C, Túnez I, Aschner M, Santamaría A. Thallium Toxicity in Caenorhabditis elegans: Involvement of the SKN-1 Pathway and Protection by S-Allylcysteine. Neurotox Res. 2020 Aug;38(2):287-298. doi: 10.1007/s12640-020-00220-1. Epub 2020 May 28. PMID: 32468422.

3. Elmazoglu Z, Rangel-López E, Medina-Campos ON, Pedraza-Chaverri J, Túnez I, Aschner M, Santamaría A, Karasu Ç. Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neurons. Neurochem Int. 2020 Nov;140:104817. doi: 10.1016/j.neuint.2020.104817. Epub 2020 Aug 8. PMID: 32781098; PMCID: PMC7572748.

4. Ozlu H, Cakir Gundogdu A, Elmazoglu Z, Take Kaplanoglu G, Oktar L, Karasu C. Bacopa Monnieri Protects the Directly Affected Organ as Well as Distant Organs Against I/R Injury by Modulating Anti-Inflammatory and Anti-Nitrosative Pathways in A Rat Model for Infra-Renal Aortic Occlusion. J Invest Surg. 2020 Jan 31:1-12. doi: 10.1080/08941939.2020.1716118. Epub ahead of print. PMID: 32003261.

5. Elmazoglu Z, Bek ZA, Sarıbaş GS, Özoğul C, Goker B, Bitik B, Aktekin CN, Karasu Ç. TLR4, RAGE, and p-JNK/JNK mediated inflammatory aggression in osteoathritic human chondrocytes are counteracted by redox-sensitive phenolic olive compounds: Comparison with ibuprofen. J Tissue Eng Regen Med. 2020 Dec;14(12):1841-1857. doi: 10.1002/term.3138. Epub 2020 Oct 5. PMID: 33010113.

6. Elmazoglu Z, Prnova MS, Santamaria A, Stefek M, Karasu C. Combatting Nitrosative Stress and Inflammation with Novel Substituted Triazinoindole Inhibitors of Aldose Reductase in PC12 Cells Exposed to 6-Hydroxydopamine Plus High Glucose. Neurotox Res. 2021 Apr;39(2):210-226. doi: 10.1007/s12640-020-00305-x. Epub 2020 Nov 4. PMID: 33146867.

7. Ergin V, Hariry RE, Karasu C. Carbonyl stress in aging process: role of vitamins and phytochemicals as redox regulators. Aging Dis. 2013 Oct 1;4(5):276-94. doi: 10.14336/AD.2013.0400276. PMID: 24124633; PMCID: PMC3794724.

8. Elmazoglu Z, Yar Saglam AS, Sonmez C, Karasu C. Luteolin protects microglia against rotenone-induced toxicity in a hormetic manner through targeting oxidative stress response, genes associated with Parkinson's disease and inflammatory pathways. Drug Chem Toxicol. 2020 Jan;43(1):96-103. doi: 10.1080/01480545.2018.1504961. Epub 2018 Sep 12. PMID: 30207190.

9. Aguilera-Portillo G, Rangel-López E, Villeda-Hernández J, Chavarría A, Castellanos P, Elmazoglu Z, Karasu Ç, Túnez I, Pedraza G, Königsberg M, Santamaría A. The Pharmacological Inhibition of Fatty Acid Amide Hydrolase Prevents Excitotoxic Damage in the Rat Striatum: Possible Involvement of CB1 Receptors Regulation. Mol Neurobiol. 2019 Feb;56(2):844-856. doi: 10.1007/s12035-018-1129-2. Epub 2018 May 25. PMID: 29802570.

10. Ulusu NN, Gök M, Sayin Şakul AA, Ari N, Stefek M, Karasu Ç; “The ADIC (Antioxidants in Diabetes-Induced Complications) Study Group”. Antioxidant SMe1EC2 modulates pentose phosphate pathway and glutathione-dependent enzyme activities in tissues of aged diabetic rats. Interdiscip Toxicol. 2017 Dec;10(4):148-154. doi: 10.1515/intox-2017-0021. Epub 2018 Mar 1. PMID: 30147422; PMCID: PMC6102677.

11. Elmazoglu Z, Ergin V, Sahin E, Kayhan H, Karasu C. Oleuropein and rutin protect against 6-OHDA-induced neurotoxicity in PC12 cells through modulation of mitochondrial function and unfolded protein response. Interdiscip Toxicol. 2017 Dec;10(4):129-141. doi: 10.1515/intox-2017-0019. Epub 2018 Mar 1. PMID: 30147420; PMCID: PMC6102676.

12. Karasu C, Cumaoğlu A, Gürpinar AR, Kartal M, Kovacikova L, Milackova I, Stefek M. Aldose reductase inhibitory activity and antioxidant capacity of pomegranate extracts. Interdiscip Toxicol. 2012 Mar;5(1):15-20. doi: 10.2478/v10102-012-0003-8. PMID: 22783144; PMCID: PMC3389504.

13. Gök M, Ulusu NN, Tarhan N, Tufan C, Ozansoy G, Arı N, Karasu Ç. Flaxseed Protects Against Diabetes-Induced Glucotoxicity by Modulating Pentose Phosphate Pathway and Glutathione-Dependent Enzyme Activities in Rats. J Diet Suppl. 2016;13(3):339-51. doi: 10.3109/19390211.2015.1036188. Epub 2015 Aug 28. PMID: 26317558.

14. Şakul A, Arı N, Sotnikova R, Ozansoy G, Karasu Ç. A pyridoindole antioxidant SMe1EC2 regulates contractility, relaxation ability, cation channel activity, and protein-carbonyl modifications in the aorta of young and old rats with or without diabetes mellitus. Geroscience. 2018 Aug;40(4):377-392. doi: 10.1007/s11357-018-0034-y. Epub 2018 Jul 27. PMID: 30054861; PMCID: PMC6136298.

15. Bali EB, Ergin V, Rackova L, Bayraktar O, Küçükboyaci N, Karasu Ç. Olive leaf extracts protect cardiomyocytes against 4-hydroxynonenal-induced toxicity in vitro: comparison with oleuropein, hydroxytyrosol, and quercetin. Planta Med. 2014 Aug;80(12):984-92. doi: 10.1055/s-0034-1382881. Epub 2014 Aug 6. PMID: 25098929.

16. Sakul A, Cumaoğlu A, Aydin E, Ari N, Dilsiz N, Karasu C. Age- and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: consequences of treatment with antioxidant pyridoindole. Exp Gerontol. 2013 May;48(5):476-84. doi: 10.1016/j.exger.2013.02.028. Epub 2013 Mar 5. PMID: 23470276.

17. Karasu C. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. Open Cardiovasc Med J. 2010 Nov 26;4:240-56. doi: 10.2174/1874192401004010240. PMID: 21270942; PMCID: PMC3026340.

18. Elmazoglu Z, Galván-Arzate S, Aschner M, Rangel-López E, Bayraktar O, Santamaría A, Karasu Ç. Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ1-42 peptide. Neurochem Int. 2021 May;145:104993. doi: 10.1016/j.neuint.2021.104993. Epub 2021 Feb 19. PMID: 33610590.

19. Skalska S, Kyselova Z, Gajdosikova A, Karasu C, Stefek M, Stolc S. Protective effect of stobadine on NCV in streptozotocin-diabetic rats: augmentation by vitamin E. Gen Physiol Biophys. 2008 Jun;27(2):106-14. PMID: 18645225.